{"id":15937,"date":"2021-02-16T16:51:42","date_gmt":"2021-02-16T16:51:42","guid":{"rendered":"https:\/\/arsco.org\/articles\/article-detail-1862\/"},"modified":"2021-02-16T16:51:42","modified_gmt":"2021-02-16T16:51:42","slug":"article-detail-1862","status":"publish","type":"articles","link":"https:\/\/arsco.org\/en\/articles\/article-detail-15937\/","title":{"rendered":"\u0644\u0644\u0645\u0632\u064a\u062f \u0645\u0646 \u0627\u0644\u062a\u0642\u064a\u064a\u0645 \u0627\u0644\u0639\u0644\u0645\u064a \u0627\u0644\u0645\u062a\u062c\u0631\u062f \u0644\u0644\u0642\u0627\u062d\u0627\u062a \u0643\u0648\u0631\u0648\u0646\u0627"},"content":{"rendered":"<p dir=\"RTL\" style=\"text-align: justify;\"><span style=\"color:#008080;\">\u0645\u0639 \u0627\u0646\u0637\u0644\u0627\u0642 \u062d\u0645\u0644\u0627\u062a \u0627\u0644\u062a\u0644\u0642\u064a\u062d \u0636\u062f \u0643\u0648\u0631\u0648\u0646\u0627\u060c \u0645\u0646 \u0627\u0644\u0645\u0646\u0635\u0641 \u0623\u0646 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\u0638\u0647\u0648\u0631 \u0639\u0648\u0627\u0631\u0636 \u0643\u0648\u0631\u0648\u0646\u0627 &ndash; \u0633\u0648\u0627\u0621 \u0645\u0639 \u0623\u0648 \u0628\u062f\u0648\u0646 \u0646\u062a\u064a\u062c\u0629 \u0625\u064a\u062c\u0627\u0628\u064a\u0629 \u0644\u0641\u062d\u0635 <span dir=\"LTR\">PCR<\/span> &ndash; \u0642\u062f \u064a\u0639\u0627\u062f\u0644 \u0627\u0646\u062e\u0641\u0627\u0636\u0627\u064b \u0628\u0646\u0633\u0628\u0629 \u0661\u0669%\u060c \u0623\u064a \u0623\u0642\u0644 \u0628\u0643\u062b\u064a\u0631 \u0645\u0646 \u0639\u064e\u062a\u0628\u0629 \u0627\u0644\u0641\u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u0628\u0627\u0644\u063a\u0629 \u0665\u0660% \u0644\u0646\u064a\u0644 \u0627\u0644\u062a\u0631\u062e\u064a\u0635 \u0627\u0644\u0630\u064a \u062d\u062f\u062f\u0647 \u0627\u0644\u0645\u0646\u0638\u0645\u0648\u0646&quot; (\u0663).<\/p>\n<p dir=\"RTL\" style=\"text-align: justify;\">\u0645\u0646 \u0627\u0644\u0645\u0647\u0645 \u0623\u064a\u0636\u0627\u064b 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\u0645\u0646\u0647\u0627.<\/p>\n<p dir=\"RTL\" style=\"text-align: justify;\">\u0646\u0623\u062a\u064a \u0627\u0644\u0622\u0646 \u0639\u0644\u0649 \u0630\u0643\u0631 \u0645\u0639\u0627\u064a\u064a\u0631 \u0627\u0644\u0633\u0644\u0627\u0645\u0629\u060c \u0648\u0647\u064a \u0627\u0644\u062a\u064a \u0639\u0627\u062f\u0629 \u0645\u0627 \u062a\u0624\u062e\u0631 \u0635\u062f\u0648\u0631 \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0629 \u0648\u0625\u0639\u0637\u0627\u0621 \u0627\u0644\u062a\u0631\u0627\u062e\u064a\u0635 \u0644\u0644\u0642\u0627\u062d\u0627\u062a \u0625\u0644\u0649 \u0639\u062f\u0629 \u0633\u0646\u0648\u0627\u062a. \u0648\u0628\u0645\u0627 \u0623\u0646 \u0644\u0642\u0627\u062d\u064e\u064a\u0652 \u0641\u0627\u064a\u0632\u0631\/\u0628\u064a\u0648\u0646\u062a\u0643 \u0648\u0645\u0648\u062f\u0631\u0646\u0627 \u0647\u0645\u0627 \u0627\u0644\u0623\u0633\u0628\u0642 \u0627\u0646\u062a\u0634\u0627\u0631\u0627\u064b \u0648\u0627\u0644\u0623\u0643\u062b\u0631 \u0625\u062b\u0627\u0631\u0629\u064b \u0644\u0644\u062c\u062f\u0644 \u0644\u0627\u0639\u062a\u0645\u0627\u062f\u0647\u0645\u0627 \u062a\u0642\u0646\u064a\u0629 <span dir=\"LTR\">mRNA<\/span>\u060c \u0641\u0625\u0646\u0646\u0627 \u0646\u062d\u0635\u0631 \u0627\u0644\u0646\u0642\u0627\u0634 \u0641\u064a\u0647\u0645\u0627 \u0647\u0646\u0627. \u064a\u0634\u064a\u0631 \u0645\u0642\u0627\u0644 \u0641\u064a \u062f\u0648\u0631\u064a\u0629 <span dir=\"LTR\">NEJM<\/span> (\u0663\u0660 \u0643\u0627\u0646\u0648\u0646 \u0627\u0644\u0623\u0648\u0644 \u0662\u0660\u0662\u0660) \u0625\u0644\u0649 \u0623\u0646\u0647 &quot;\u0628\u0627\u0644\u0631\u063a\u0645 \u0645\u0646 \u0623\u0646 \u062a\u0642\u0646\u064a\u0629 <span dir=\"LTR\">mRNA<\/span> \u0644\u064a\u0633\u062a \u062c\u062f\u064a\u062f\u0629\u060c \u0625\u0644\u0627 \u0623\u0646\u0647 \u0644\u064a\u0633 \u0647\u0646\u0627\u0643 \u0623\u064a \u0644\u0642\u0627\u062d \u0645\u0631\u062e\u0635 \u0644\u0647\u0630\u0647 \u0627\u0644\u062a\u0642\u0646\u064a\u0629\u060c \u0648\u0625\u0646 \u0644\u0642\u0627\u062d\u064e\u064a\u0652 \u0641\u0627\u064a\u0632\u0631\/\u0628\u064a\u0648\u0646\u062a\u0643 \u0648\u0645\u0648\u062f\u0631\u0646\u0627 \u0647\u0645\u0627 \u0627\u0644\u0623\u0648\u0644\u0627\u0646 \u0627\u0644\u0644\u0630\u0627\u0646 \u0646\u0627\u0644\u0627 \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0629 \u0644\u0644\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u0637\u0627\u0631\u0626&quot;. \u064a\u0634\u064a\u0631 \u0627\u0644\u0645\u0642\u0627\u0644 \u0646\u0641\u0633\u0647 \u0625\u0644\u0649 \u0623\u0646 \u0628\u0639\u062f \u062a\u0644\u0642\u064a\u062d \u062d\u0648\u0627\u0644\u064a \u0645\u0644\u064a\u0648\u0646\u064a \u0639\u0627\u0645\u0644 \u0641\u064a \u0627\u0644\u0642\u0637\u0627\u0639 \u0627\u0644\u0635\u062d\u064a \u0641\u064a \u0627\u0644\u0648\u0644\u0627\u064a\u0627\u062a \u0627\u0644\u0645\u062a\u062d\u062f\u0629 \u0628\u0644\u0642\u0627\u062d \u0641\u0627\u064a\u0632\u0631\/\u0628\u064a\u0648\u0646\u062a\u0643\u060c \u0648\u0635\u0644\u062a \u0646\u0633\u0628\u0629 \u062d\u062f\u0648\u062b \u0635\u062f\u0645\u0629 \u062d\u0633\u0627\u0633\u064a\u0629 \u0645\u0641\u0631\u0637\u0629<span dir=\"LTR\">(anaphylaxis) <\/span>&nbsp;\u0625\u0644\u0649 \u062d\u0627\u0644\u0629 \u0644\u0643\u0644 \u0645\u0626\u0629 \u0623\u0644\u0641 \u0634\u062e\u0635 \u0645\u0645\u0646 \u0623\u062e\u0630\u0648\u0627 \u0627\u0644\u0644\u0642\u0627\u062d\u060c \u0648\u0647\u064a \u0623\u0639\u0644\u0649 \u0628\u0639\u0634\u0631\u0629 \u0645\u0631\u0627\u062a \u062a\u0642\u0631\u064a\u0628\u0627\u064b \u0645\u0646 \u0627\u0644\u0644\u0642\u0627\u062d\u0627\u062a \u0627\u0644\u0633\u0627\u0628\u0642\u0629. \u0648\u0642\u062f \u062a\u0643\u0648\u0646 \u0645\u0627\u062f\u0629 <span dir=\"LTR\">PEG 2000<\/span> \u0627\u0644\u0645\u062b\u0628\u062a\u0629 \u0644\u063a\u0644\u0627\u0641 \u0627\u0644\u0644\u0642\u0627\u062d \u0627\u0644\u062f\u0647\u0646\u064a \u0647\u064a \u0627\u0644\u0645\u0633\u0624\u0648\u0644\u0629 \u0639\u0646 \u0631\u062f\u0629 \u0641\u0639\u0644 \u0627\u0644\u0645\u0646\u0627\u0639\u0629 \u0647\u0630\u0647. \u0627\u0644\u062c\u062f\u064a\u0631 \u0628\u0627\u0644\u0630\u0643\u0631 \u0623\u0646 &quot;\u0644\u0627 \u0644\u0642\u0627\u062d \u0622\u062e\u0631 \u062d\u062a\u0649 \u0627\u0644\u0622\u0646 \u064a\u062d\u0648\u064a \u0645\u0627\u062f\u0629 <span dir=\"LTR\">PEG<\/span> \u0642\u062f \u062a\u0645 \u062a\u062f\u0627\u0648\u0644\u0647 \u0639\u0644\u0649 \u0646\u0637\u0627\u0642 \u0648\u0627\u0633\u0639&quot;. \u0648\u0644\u0627 \u064a\u062e\u0644\u0648 \u0627\u0644\u0623\u0645\u0631 \u0645\u0646 \u0627\u062d\u062a\u0645\u0627\u0644 \u0643\u0648\u0646 \u0641\u0626\u0627\u062a \u0633\u0643\u0627\u0646\u064a\u0629 \u0623\u062e\u0631\u0649 (\u063a\u064a\u0631 \u0627\u0644\u062a\u064a \u0623\u062c\u0631\u064a\u062a \u0639\u0644\u064a\u0647\u0627 \u0627\u0644\u062a\u062c\u0627\u0631\u0628) \u0623\u0643\u062b\u0631 \u0639\u0631\u0636\u0629 \u0644\u062a\u062d\u0641\u064a\u0632 \u0631\u062f\u0629 \u0641\u0639\u0644 \u0645\u0646\u0627\u0639\u064a\u0629 \u0623\u0642\u0648\u0649 \u0644\u0648\u062c\u0648\u062f \u0647\u0630\u0647 \u0627\u0644\u0645\u0627\u062f\u0629\u060c \u0648\u0647\u0643\u0630\u0627 \u0645\u0639 \u0633\u0627\u0626\u0631 &quot;\u0627\u0644\u0623\u062d\u062f\u0627\u062b \u0627\u0644\u0633\u0644\u0628\u064a\u0629&quot; \u0627\u0644\u0645\u062d\u062a\u0645\u0644\u0629 \u0627\u0644\u0623\u062e\u0631\u0649 \u0627\u0644\u062a\u064a \u0644\u0627 \u0633\u0628\u064a\u0644 \u0644\u0644\u062a\u062c\u0627\u0631\u0628 \u0625\u0644\u0649 \u062a\u0648\u0642\u0639\u0647\u0627 (\u0666).<\/p>\n<p dir=\"RTL\" style=\"text-align: justify;\">\u0645\u0646 \u0627\u0644\u0639\u0648\u0627\u0631\u0636 \u0627\u0644\u0645\u062b\u064a\u0631\u0629 \u0644\u0644\u0642\u0644\u0642 \u0623\u064a\u0636\u0627\u064b \u0645\u0627 \u064a\u064f\u0635\u0637\u0644\u062d \u0639\u0644\u064a\u0647 \u0628\u0627\u0633\u0645 &quot;\u0627\u0644\u0645\u0631\u0636 \u0627\u0644\u0645\u0639\u0632\u0651\u0632 \u0627\u0644\u0645\u0631\u062a\u0628\u0637 \u0628\u0627\u0644\u0644\u0642\u0627\u062d&quot; <span dir=\"LTR\">(Vaccine-associated enhanced disease)<\/span>\u060c \u0648\u0627\u0644\u0630\u064a \u064a\u0639\u0646\u064a \u0632\u064a\u0627\u062f\u0629 \u0641\u064a \u062d\u062f\u0629 \u0627\u0644\u0645\u0631\u0636 \u0639\u0646\u062f \u0645\u0646 \u0633\u064a\u0635\u0627\u0628 \u0628\u0627\u0644\u0641\u064a\u0631\u0648\u0633 \u0628\u0639\u062f \u0623\u062e\u0630 \u0627\u0644\u0644\u0642\u0627\u062d. \u0648\u0641\u064a \u062d\u064a\u0646 \u0623\u0646 \u0647\u0630\u0647 \u0627\u0644\u0638\u0627\u0647\u0631\u0629 \u0644\u0645 \u062a\u064f\u0633\u064e\u062c\u0651\u064e\u0644 \u0641\u064a \u0623\u0651\u064a\u0651\u064d \u0645\u0646 \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u062d\u062a\u0649 \u0627\u0644\u0622\u0646\u060c \u0641\u0642\u062f \u064a\u0639\u0648\u062f \u0630\u0644\u0643 \u0625\u0644\u0649 \u0631\u0635\u062f \u0639\u062f\u062f \u0642\u0644\u064a\u0644 \u062c\u062f\u0627\u064b \u0645\u0646 \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0627\u0644\u0634\u062f\u064a\u062f\u0629 \u0644\u0644\u0645\u0631\u0636 \u0641\u064a \u0647\u0630\u0647 \u0627\u0644\u062a\u062c\u0627\u0631\u0628 (\u0641\u0627\u064a\u0632\u0631\/\u0628\u064a\u0648\u0646\u062a\u0643: \u0669 \u062d\u0627\u0644\u0627\u062a \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0648\u0647\u0645\u064a \u0648\u062d\u0627\u0644\u0629 \u0648\u0627\u062d\u062f\u0629 \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0644\u0642\u0627\u062d\u061b \u0645\u0648\u062f\u0631\u0646\u0627: \u0663\u0660 \u062d\u0627\u0644\u0629 \u0643\u0644\u0647\u0627 \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0648\u0647\u0645\u064a). \u0648\u0641\u064a \u062d\u064a\u0646 \u0623\u0646 \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0633\u062a\u0631\u0627\u0642\u0628 \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u064a\u0646 \u062d\u062a\u0649 \u0639\u0627\u0645 \u0648\u0627\u062d\u062f \u0639\u0644\u0649 \u0627\u0644\u0623\u0642\u0644 \u0628\u0639\u062f \u0627\u0644\u062a\u062c\u0631\u0628\u0629\u060c \u064a\u0646\u0628\u0647 \u0645\u0642\u0627\u0644 \u0641\u064a \u062f\u0648\u0631\u064a\u0629 <span dir=\"LTR\">Science Translational Medicine<\/span> (\u0664 \u062a\u0634\u0631\u064a\u0646 \u0627\u0644\u062b\u0627\u0646\u064a \u0662\u0660\u0662\u0660) \u0625\u0644\u0649 \u0623\u0646\u0647 \u0628\u0646\u0627\u0621\u064b \u0639\u0644\u0649 \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0629 \u0627\u0644\u0645\u0628\u062f\u0626\u064a\u0629 \u0644\u0644\u0642\u0627\u062d\u0627\u062a\u060c &quot;\u062a\u0645 \u062a\u0633\u0631\u064a\u0639 \u0639\u0645\u0644\u064a\u0629 \u0625\u0646\u062a\u0627\u062c \u0648\u062a\u0648\u0632\u064a\u0639 \u0627\u0644\u0645\u0644\u0627\u064a\u064a\u0646 \u0645\u0646 \u0627\u0644\u0644\u0642\u0627\u062d\u0627\u062a \u0644\u0644\u0633\u064a\u0637\u0631\u0629 \u0639\u0644\u0649 \u0627\u0644\u0648\u0628\u0627\u0621. \u0644\u0630\u0644\u0643\u060c \u0641\u0625\u0646 \u0627\u0644\u0643\u062b\u064a\u0631\u064a\u0646 \u0633\u064a\u062a\u0644\u0642\u0648\u0646 \u0627\u0644\u0644\u0642\u0627\u062d \u0642\u0628\u0644 \u0623\u0646 \u062a\u0646\u062a\u0647\u064a \u0639\u0645\u0644\u064a\u0629 \u0627\u0644\u0645\u0631\u0627\u0642\u0628\u0629 \u0637\u0648\u064a\u0644\u0629 \u0627\u0644\u0623\u0645\u062f \u0644\u0644\u062a\u062c\u0627\u0631\u0628&quot; (\u0667). \u0648\u0627\u0644\u0623\u0643\u062b\u0631 \u063a\u0631\u0627\u0628\u0629 \u0645\u0627 \u0623\u0639\u0644\u0646\u062a\u0647 \u062a\u062c\u0631\u0628\u0629 \u0641\u0627\u064a\u0632\u0631\/\u0628\u064a\u0648\u0646\u062a\u0643 \u0628\u0639\u062f \u0630\u0644\u0643 (\u0661\u0660 \u0643\u0627\u0646\u0648\u0646 \u0627\u0644\u0623\u0648\u0644 \u0662\u0660\u0662\u0660) \u0645\u0646 \u0623\u0646\u0647 &quot;\u0628\u0627\u0644\u0631\u063a\u0645 \u0645\u0646 \u0623\u0646 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u062a\u0645 \u062a\u0635\u0645\u064a\u0645\u0647\u0627 \u0644\u0645\u062a\u0627\u0628\u0639\u0629 \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u064a\u0646 \u0644\u062f\u0648\u0627\u0639\u064a \u0627\u0644\u0633\u0644\u0627\u0645\u0629 \u0648\u0627\u0644\u0641\u0639\u0627\u0644\u064a\u0629 \u062d\u062a\u0649 \u0633\u0646\u062a\u064a\u0646 \u0628\u0639\u062f \u0627\u0644\u062c\u0631\u0639\u0629 \u0627\u0644\u062b\u0627\u0646\u064a\u0629\u060c \u0646\u0638\u0631\u0627\u064b \u0644\u0644\u0641\u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u0639\u0627\u0644\u064a\u0629 \u0644\u0644\u0651\u0642\u0627\u062d\u060c \u0641\u0625\u0646 \u0627\u0644\u0639\u0648\u0627\u0626\u0642 \u0627\u0644\u0623\u062e\u0644\u0627\u0642\u064a\u0629 \u0648\u0627\u0644\u0639\u064e\u0645\u0644\u064a\u0629 \u062a\u062d\u0648\u0644 \u062f\u0648\u0646 \u0645\u062a\u0627\u0628\u0639\u0629 \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u064a\u0646 \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0648\u0647\u0645\u064a \u0644\u0645\u062f\u0629 \u0633\u0646\u062a\u064a\u0646 \u062f\u0648\u0646 \u0645\u0646\u062d\u0647\u0645 \u0627\u0644\u062a\u0644\u0642\u064a\u062d \u0627\u0644\u0641\u0639\u0651\u0627\u0644\u060c \u0630\u0644\u0643 \u0628\u0639\u062f \u0623\u0646 \u062a\u062a\u0645 \u0645\u0648\u0627\u0641\u0642\u0629 \u0627\u0644\u0645\u0646\u0638\u0645\u0648\u0646 \u0639\u0644\u0649 \u0627\u0644\u0644\u0642\u0627\u062d \u0648\u062a\u0648\u0635\u064a \u0628\u0647 \u0647\u064a\u0626\u0627\u062a \u0627\u0644\u0635\u062d\u0629 \u0627\u0644\u0639\u0627\u0645\u0629&quot; (\u0668). \u0648\u0639\u0644\u064a\u0647\u060c \u0644\u0646 \u064a\u0643\u0648\u0646 \u0628\u0627\u0644\u0625\u0645\u0643\u0627\u0646 \u0645\u0642\u0627\u0631\u0646\u0629 \u0623\u064a \u0645\u0646 \u0627\u0644\u0639\u0648\u0627\u0631\u0636 \u0645\u0639 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0648\u0647\u0645\u064a\u060c \u0628\u0644 \u0625\u0646 \u062c\u0645\u064a\u0639 \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u064a\u0646 \u0641\u064a \u0627\u0644\u062a\u062c\u0631\u0628\u0629 \u0633\u064a\u062a\u0644\u0642\u0648\u0646 \u0627\u0644\u0644\u0642\u0627\u062d.<\/p>\n<p dir=\"RTL\" style=\"text-align: justify;\">\u0648\u064a\u0628\u0642\u0649 \u0627\u0644\u0647\u0627\u062c\u0633 \u0627\u0644\u0623\u0643\u0628\u0631 (\u0628\u0646\u0638\u0631 \u0643\u0627\u062a\u0628 \u0647\u0630\u0627 \u0627\u0644\u0645\u0642\u0627\u0644) \u0647\u0648 \u0623\u0646 \u0647\u0630\u0647 \u0627\u0644\u0644\u0642\u0627\u062d\u0627\u062a \u062a\u062a\u0639\u0645\u0651\u062f \u062a\u0646\u0634\u064a\u0637 \u0627\u0644\u062c\u0647\u0627\u0632 \u0627\u0644\u0645\u0646\u0627\u0639\u064a \u0639\u0646\u062f \u0627\u0644\u0641\u0626\u0629 \u0627\u0644\u0623\u063a\u0644\u0628 \u0645\u0646 \u0627\u0644\u0646\u0627\u0633 \u0639\u0644\u0649 \u0646\u062d\u0648 \u0623\u0642\u0648\u0649 \u0645\u0646 \u0625\u0635\u0627\u0628\u062a\u0647\u0645 \u0637\u0628\u064a\u0639\u064a\u0627\u064b \u0628\u0627\u0644\u0641\u064a\u0631\u0648\u0633. \u0648\u0643\u0627\u0646 \u0642\u062f \u0623\u0634\u0627\u0631 \u0628\u062d\u062b \u0641\u064a \u062f\u0648\u0631\u064a\u0629 <span dir=\"LTR\">Nature Communications<\/span> (\u0662\u0665 \u062a\u0634\u0631\u064a\u0646 \u0627\u0644\u062b\u0627\u0646\u064a \u0662\u0660\u0662\u0660) \u0625\u0644\u0649 \u0623\u0646 \u0627\u0644\u0637\u0641\u0631\u0627\u062a \u0641\u064a \u0641\u064a\u0631\u0648\u0633 \u0643\u0648\u0631\u0648\u0646\u0627 \u0642\u062f \u062a\u0646\u0634\u0623 \u0628\u0645\u0633\u0627\u0639\u062f\u0629 \u0627\u0644\u062c\u0647\u0627\u0632 \u0627\u0644\u0645\u0646\u0627\u0639\u064a \u0644\u062c\u0633\u0645 \u0627\u0644\u0625\u0646\u0633\u0627\u0646 \u0639\u0628\u0631 \u0639\u0645\u0644\u064a\u0629 \u062a\u0639\u062f\u064a\u0644 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0644\u0644\u0641\u064a\u0631\u0648\u0633 <span dir=\"LTR\">RNA editing<\/span> (\u0669). \u0641\u0644\u0627 \u0646\u062f\u0631\u064a \u0625\u0630\u0627 \u0645\u0627 \u0643\u0627\u0646 \u0627\u062e\u062a\u0644\u0627\u0644 \u0627\u0644\u062a\u0648\u0627\u0632\u0646 \u0644\u062c\u0647\u0629 \u062a\u062d\u0641\u064a\u0632 \u0645\u0646\u0627\u0639\u064a \u0623\u0642\u0648\u0649 \u0636\u062f \u0627\u0644\u0641\u064a\u0631\u0648\u0633 (\u0639\u0628\u0631 \u062a\u0644\u0642\u064a \u0627\u0644\u0644\u0642\u0627\u062d) \u0633\u064a\u0646\u0637\u0648\u064a \u0639\u0644\u0649 \u0646\u0634\u0648\u0621 \u0637\u0641\u0631\u0627\u062a \u0623\u0643\u062b\u0631 \u0644\u0644\u0641\u064a\u0631\u0648\u0633 \u0645\u0645\u0627 \u0644\u0648 \u0627\u0633\u062a\u0645\u0631\u062a \u0627\u0644\u0625\u0635\u0627\u0628\u0627\u062a \u0637\u0628\u064a\u0639\u064a\u0629 \u0628\u062f\u0648\u0646 \u062a\u062f\u062e\u0644. \u0643\u0645\u0627 \u0623\u0646 \u0645\u0646 \u0627\u0644\u0639\u0648\u0627\u0642\u0628 \u0645\u0627 \u0644\u0645 \u064a\u062a\u0645 \u0627\u0644\u0627\u0644\u062a\u0641\u0627\u062a \u0625\u0644\u064a\u0647\u0627 \u0628\u0634\u0643\u0644 \u0643\u0627\u0641\u060c \u0643\u0623\u0646 \u064a\u062a\u0633\u0644\u0644 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0627\u0644\u0645\u0631\u0633\u0627\u0644 \u0644\u0644\u0642\u0627\u062d \u0625\u0644\u0649 \u0646\u0648\u0627\u0629 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0633\u0645 \u0648\u064a\u062a\u0645 \u062f\u0645\u062c\u0647 \u0645\u0639 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0627\u0644\u0628\u0634\u0631\u064a. \u0648\u0628\u0639\u064a\u062f\u0627\u064b \u0639\u0646 \u0646\u0638\u0631\u064a\u0627\u062a \u0627\u0644\u062a\u0644\u0627\u0639\u0628 \u0628\u0627\u0644\u062c\u064a\u0646\u0627\u062a\u060c \u0641\u0645\u0646 \u0627\u0644\u0645\u062d\u062a\u0645\u0644 \u0623\u0646 \u062a\u062a\u0645 \u0647\u0630\u0647 \u0627\u0644\u0639\u0645\u0644\u064a\u0629 \u0639\u0628\u0631 \u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a<span dir=\"LTR\">Reverse Transcriptase<\/span> \u0627\u0644\u0645\u0639\u0631\u0648\u0641\u0629 \u0628\u0648\u062c\u0648\u062f\u0647\u0627 \u0641\u064a \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0628\u0634\u0631\u064a\u0629\u060c \u0648\u0627\u0644\u062a\u064a \u0627\u0631\u062a\u0628\u0637 \u0639\u0645\u0644 \u0628\u0639\u0636\u0647\u0627 \u0628\u062a\u062d\u0648\u0644 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0625\u0644\u0649 \u0633\u0631\u0637\u0627\u0646\u064a\u0629. \u0648\u0641\u064a \u062d\u064a\u0646 \u064a\u0634\u064a\u0631 \u0623\u0633\u062a\u0627\u0630 \u0639\u0644\u0645 \u0627\u0644\u062c\u0631\u0627\u062b\u064a\u0645 \u0641\u064a \u062c\u0627\u0645\u0639\u0629 \u0643\u0648\u0644\u0648\u0645\u0628\u064a\u0627 \u0627\u0644\u0628\u0631\u064a\u0637\u0627\u0646\u064a\u0629 \u062f. \u0646\u064a\u0641\u064a\u0648 \u0633\u064a\u0645\u0648\u0644\u0627\u064a \u0625\u0644\u0649 \u0623\u0646 \u0647\u0630\u0647 \u0627\u0644\u0645\u062e\u0627\u0648\u0641 \u0646\u0638\u0631\u064a\u0629 \u0625\u0644\u0649 \u0627\u0644\u0622\u0646\u060c \u0625\u0644\u0627 \u0623\u0646\u0647 &quot;\u062d\u062a\u0649 \u064a\u062a\u0645 \u0627\u062e\u062a\u0628\u0627\u0631 \u0647\u0630\u0647 \u0627\u0644\u0645\u062e\u0627\u0648\u0641 \u0623\u0648 \u0645\u0631\u0627\u0642\u0628\u062a\u0647\u0627 \u0628\u0639\u062f \u0627\u0644\u062a\u0644\u0642\u064a\u062d \u0623\u0648 \u0627\u0644\u0625\u0635\u0627\u0628\u0629 \u0627\u0644\u0637\u0628\u064a\u0639\u064a\u0629\u060c \u0644\u0627 \u0628\u062f \u0644\u0644\u062a\u0642\u064a\u064a\u0645\u0627\u062a \u0627\u0644\u062a\u0646\u0638\u064a\u0645\u064a\u0629 \u0627\u0644\u062e\u0627\u0635\u0629 \u0628\u0644\u0642\u0627\u062d\u0627\u062a <span dir=\"LTR\">RNA<\/span> \u0645\u0646 \u0623\u0646 \u062a\u0646\u0637\u0648\u064a \u0639\u0644\u0649 \u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u0633\u0645\u0651\u064a\u0651\u0629 \u0627\u0644\u062c\u064a\u0646\u064a\u0629&quot; (\u0661\u0660).<\/p>\n<div>\n<p dir=\"RTL\" style=\"text-align: justify;\"><span style=\"color:#008080;\">\u0648\u0641\u064a \u0627\u0644\u062e\u062a\u0627\u0645\u060c \u062d\u062a\u0649 \u0644\u0648 \u0623\u0647\u0645\u0644\u0646\u0627 \u0627\u0644\u0634\u0643\u0648\u0643 \u062d\u0648\u0644 \u0641\u0639\u0627\u0644\u064a\u0629 \u0647\u0630\u0647 \u0627\u0644\u0644\u0642\u0627\u062d\u0627\u062a \u0648\u062a\u0623\u062b\u064a\u0631\u0627\u062a\u0647\u0627 \u0627\u0644\u0645\u062d\u062a\u0645\u0644\u0629 \u0639\u0644\u0649 \u0627\u0644\u0633\u0644\u0627\u0645\u0629 \u0627\u0644\u0639\u0627\u0645\u0629\u060c \u0641\u0644\u064a\u0633 \u0645\u0646 \u062f\u0644\u064a\u0644 \u0639\u0644\u0649 \u0623\u0646 \u0627\u0644\u0645\u0646\u0627\u0639\u0629 \u0627\u0644\u0645\u0643\u062a\u0633\u0628\u0629 \u062c\u0631\u0627\u0621 \u0647\u0630\u0647 \u0627\u0644\u0644\u0642\u0627\u062d\u0627\u062a \u0633\u062a\u0643\u0648\u0646 \u0637\u0648\u064a\u0644\u0629 \u0627\u0644\u0623\u0645\u062f &ndash; \u0641\u064a \u062d\u064a\u0646 \u0623\u0646 \u0627\u0644\u0645\u0646\u0627\u0639\u0629 \u0627\u0644\u0637\u0628\u064a\u0639\u064a\u0629 \u0645\u062b\u0644\u0627\u064b \u062a\u0633\u062a\u0645\u0631 \u0644\u0623\u0643\u062b\u0631 \u0645\u0646 \u0633\u062a\u0629 \u0623\u0634\u0647\u0631 (\u0664) &ndash; \u0645\u0639 \u0627\u0644\u062a\u0623\u0643\u064a\u062f \u0639\u0644\u0649 \u0639\u062f\u0645 \u0627\u062e\u062a\u0628\u0627\u0631 \u0641\u0639\u0627\u0644\u064a\u062a\u0647\u0627 \u062e\u0635\u064a\u0635\u0627\u064b \u0644\u062f\u0649 \u0643\u0628\u0627\u0631 \u0627\u0644\u0633\u0646 \u0648\u0627\u0644\u0636\u0639\u0641\u0627\u0621 \u0645\u0646\u0627\u0639\u064a\u0627\u064b\u060c \u0648\u0647\u0645 \u0623\u0643\u062b\u0631 \u0645\u0646 \u064a\u064f\u062e\u0634\u0649 \u0636\u0631\u0631\u0647\u0645 \u062c\u0631\u0627\u0621 \u0627\u0644\u0625\u0635\u0627\u0628\u0629 \u0628\u0627\u0644\u0641\u064a\u0631\u0648\u0633. \u0643\u0645\u0627 \u064a\u0646\u0628\u063a\u064a \u0627\u0644\u062a\u0646\u0628\u0647 \u0625\u0644\u0649 \u0645\u0648\u0639\u062f \u0628\u062f\u0621 \u0627\u0644\u062a\u0644\u0642\u064a\u062d \u0648\u0638\u0647\u0648\u0631 \u0622\u062b\u0627\u0631\u0647 \u0639\u0642\u0628 \u0627\u0644\u0645\u0648\u062c\u0629 \u0627\u0644\u062b\u0627\u0646\u064a\u0629 \u0641\u064a \u0645\u0639\u0638\u0645 \u0627\u0644\u0628\u0644\u062f\u0627\u0646. \u0641\u0645\u0646 \u0627\u0644\u0633\u0647\u0644 \u0623\u0646 \u064a\u064f\u0646\u0633\u064e\u0628 \u0627\u0644\u0641\u0636\u0644 \u0641\u064a \u0627\u0646\u062d\u0633\u0627\u0631 \u0627\u0646\u062a\u0634\u0627\u0631 \u0627\u0644\u0641\u064a\u0631\u0648\u0633 \u0625\u0644\u0649 \u0639\u0645\u0644 \u0627\u0644\u0644\u0642\u0627\u062d\u060c \u0641\u064a\u0645\u0627 \u064a\u0635\u0627\u062f\u0641 \u0630\u0644\u0643 \u0627\u0646\u062a\u0647\u0627\u0621 \u0627\u0644\u062a\u0623\u062b\u064a\u0631 \u0627\u0644\u0645\u0648\u0633\u0645\u064a \u0627\u0644\u0645\u062d\u062a\u0645\u0644 \u0644\u0627\u0646\u062a\u0634\u0627\u0631 \u0627\u0644\u0641\u064a\u0631\u0648\u0633 \u0627\u0644\u0630\u064a \u064a\u0642\u0639 \u062d\u0635\u0631\u0627\u064b \u0641\u064a \u0641\u0635\u0644 \u0627\u0644\u0634\u062a\u0627\u0621\u060c \u0623\u064a \u0643\u0645\u062b\u0644 \u0633\u0627\u0626\u0631 \u0641\u064a\u0631\u0648\u0633\u0627\u062a \u0643\u0648\u0631\u0648\u0646\u0627 \u0627\u0644\u0645\u0648\u0633\u0645\u064a\u0629 \u0627\u0644\u0645\u0633\u0628\u0628\u0629 \u0644\u0644\u0631\u0634\u062d (\u0661\u0661).<\/span><br \/>\n&nbsp;<\/p>\n<hr \/>\n<p>\n<span style=\"color:#DAA520;\">\u0627\u0644\u0645\u0631\u0627\u062c\u0639<\/span><\/p>\n<\/div>\n<ol>\n<li dir=\"ltr\" style=\"text-align: left;\">These Coronavirus Trials Don&rsquo;t Answer the One Question We Need to Know | The New York Times. <a href=\"https:\/\/www.nytimes.com\/2020\/09\/22\/opinion\/covid-vaccine-coronavirus.html\">https:\/\/www.nytimes.com\/2020\/09\/22\/opinion\/covid-vaccine-coronavirus.html<\/a><\/li>\n<li dir=\"ltr\" style=\"text-align: left;\" value=\"2\">Will Covid-19 Vaccines Save Lives? Current Trials Aren&rsquo;t Designed to Tell Us | British Medical Journal. <a href=\"https:\/\/www.bmj.com\/content\/371\/bmj.m4037\">https:\/\/www.bmj.com\/content\/371\/bmj.m4037<\/a><\/li>\n<li dir=\"ltr\" style=\"text-align: left;\" value=\"3\">Peter Doshi: Pfizer and Moderna&rsquo;s &ldquo;95% effective&rdquo; vaccines &mdash; we need more details and the raw data | The BMJ Opinion. <a href=\"https:\/\/blogs.bmj.com\/bmj\/2021\/01\/04\/peter-doshi-pfizer-and-modernas-95-effective-vaccines-we-need-more-details-and-the-raw-data\/\">https:\/\/blogs.bmj.com\/bmj\/2021\/01\/04\/peter-doshi-pfizer-and-modernas-95-effective-vaccines-we-need-more-details-and-the-raw-data<span dir=\"RTL\">\/<\/span><\/a><\/li>\n<li dir=\"ltr\" style=\"text-align: left;\" value=\"4\">Development and Deployment of COVID-19 Vaccines for Those Most Vulnerable | Science Translational Medicine. <a href=\"https:\/\/stm.sciencemag.org\/content\/13\/579\/eabd1525\">https:\/\/stm.sciencemag.org\/content\/13\/579\/eabd1525<\/a><\/li>\n<li dir=\"ltr\" style=\"text-align: left;\" value=\"5\">Coronavirus Vaccine Tracker | The New York Times <a href=\"https:\/\/www.nytimes.com\/interactive\/2020\/science\/coronavirus-vaccine-tracker.html\">https:\/\/www.nytimes.com\/interactive\/2020\/science\/coronavirus-vaccine-tracker.html<\/a><\/li>\n<li dir=\"ltr\" style=\"text-align: left;\" value=\"6\">Maintaining Safety with SARS-CoV-2 Vaccines | The New England Journal of Medicine. <a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMra2035343\">https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMra2035343<\/a><\/li>\n<li dir=\"ltr\" style=\"text-align: left;\" value=\"7\">Prospects for a safe COVID-19 vaccine | Science Translational Medicine. <a href=\"https:\/\/stm.sciencemag.org\/content\/12\/568\/eabe0948\">https:\/\/stm.sciencemag.org\/content\/12\/568\/eabe0948<\/a><\/li>\n<li dir=\"ltr\" style=\"text-align: left;\" value=\"8\">Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine | The New England Journal of Medicine. <a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2034577\">https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2034577<\/a><\/li>\n<li dir=\"ltr\" style=\"text-align: left;\" value=\"9\">No Evidence for Increased Transmissibility from Recurrent Mutations in SARS-CoV-2 | Nature Communications. <a href=\"https:\/\/www.nature.com\/articles\/s41467-020-19818-2\">https:\/\/www.nature.com\/articles\/s41467-020-19818-2<\/a><\/li>\n<li dir=\"ltr\" style=\"text-align: left;\" value=\"10\">Do RNA vaccines obviate the need for genotoxicity studies? | Mutagenesis. <a href=\"https:\/\/academic.oup.com\/mutage\/article-abstract\/35\/6\/509\/5995048?redirectedFrom=fulltext\">https:\/\/academic.oup.com\/mutage\/article-abstract\/35\/6\/509\/5995048<\/a><\/li>\n<li dir=\"ltr\" style=\"text-align: left;\" value=\"11\">Interactions between seasonal human coronaviruses and implications for the SARS-CoV-2 pandemic: A retrospective study in Stockholm, Sweden, 2009-2020 | Journal of Clinical Virology. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1386653221000214\">https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1386653221000214<\/a><br \/>\n\t&nbsp;<\/li>\n<\/ol>\n<p style=\"text-align: right;\">\n<span style=\"color: rgb(218, 165, 32);\">\u062a\u0648\u0627\u0635\u0644 \u0645\u0639 \u0627\u0644\u0643\u0627\u062a\u0628:&nbsp;<\/span><a href=\"mailto:saad.o.omais@gmail.com\">saad.o.omais@gmail.com<\/a><br \/>\n&nbsp;<\/p>\n<hr \/>\n<p style=\"text-align: justify;\"><span style=\"color: rgb(255, 0, 0);\">\u064a\u0633\u0639\u062f\u0646\u0627 \u0623\u0646 \u062a\u0634\u0627\u0631\u0643\u0648\u0646\u0627 \u0623\u0631\u0627\u0626\u0643\u0645 \u0648\u062a\u0639\u0644\u064a\u0642\u0627\u062a\u0643\u0645 \u062d\u0648\u0644 \u0647\u0630\u0647\u0650 \u0627\u0644\u0645\u0642\u0627\u0644\u0629 \u0639\u0628\u0631 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