{"id":15728,"date":"2020-04-18T17:18:17","date_gmt":"2020-04-18T17:18:17","guid":{"rendered":"https:\/\/arsco.org\/articles\/article-detail-1606\/"},"modified":"2020-04-18T17:18:17","modified_gmt":"2020-04-18T17:18:17","slug":"article-detail-1606","status":"publish","type":"articles","link":"https:\/\/arsco.org\/en\/articles\/article-detail-15728\/","title":{"rendered":"\u0646\u0638\u0631\u0629 \u062c\u062f\u064a\u062f\u0629 \u0625\u0644\u0649 \u0622\u0644\u064a\u0629 \u0647\u0631\u0648\u0628 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0633\u0631\u0637\u0627\u0646\u064a\u0629 \u0645\u0646 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629"},"content":{"rendered":"<p dir=\"RTL\" style=\"text-align: justify;\"><span style=\"color:#008080;\">\u064a\u0639\u062f <\/span><a href=\"https:\/\/arsco.org\/articles\/article-detail-384\"><span style=\"color:#008080;\">\u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0645\u0646\u0627\u0639\u064a \u0644\u0644\u0633\u0631\u0637\u0627\u0646<\/span><\/a><span style=\"color:#008080;\">\u060c \u0627\u0644\u0630\u064a \u064a\u0631\u062a\u0643\u0632 \u0639\u0644\u0649 \u0645\u0633\u0627\u0639\u062f\u0629 \u0627\u0644\u062c\u0647\u0627\u0632 \u0627\u0644\u0645\u0646\u0627\u0639\u064a \u0639\u0644\u0649 \u0627\u0644\u062a\u0639\u0631\u0641 \u0639\u0644\u0649 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0633\u0631\u0637\u0627\u0646\u064a\u0629 \u0648\u0645\u0643\u0627\u0641\u062d\u062a\u0647\u0627\u060c \u0623\u062d\u062f \u0623\u0643\u062b\u0631 \u0645\u062c\u0627\u0644\u0627\u062a \u0627\u0644\u0628\u062d\u062b \u0623\u0647\u0645\u064a\u0629\u060c \u0644\u0645\u0627 \u0644\u062f\u064a\u0647 \u0645\u0646 \u0627\u0644\u0642\u062f\u0631\u0629 \u0639\u0644\u0649 \u0625\u0639\u0627\u062f\u0629 \u062a\u0634\u0643\u064a\u0644 \u0645\u0634\u0647\u062f \u0627\u0644\u0631\u0639\u0627\u064a\u0629 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0644\u0644\u0623\u0634\u062e\u0627\u0635 \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0627\u0644\u0639\u062f\u064a\u062f \u0645\u0646 \u0623\u0646\u0648\u0627\u0639 \u0627\u0644\u0633\u0631\u0637\u0627\u0646. \u0648\u0643\u0630\u0644\u0643 \u062a\u062d\u064a\u064a\u062f \u0648\u062a\u0639\u0637\u064a\u0644 \u0622\u0644\u064a\u0627\u062a \u0627\u0644\u062a\u0647\u0631\u0628 \u0648\u0627\u0644\u0645\u0631\u0627\u0648\u063a\u0629 \u0644\u062f\u0649 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0633\u0631\u0637\u0627\u0646\u064a\u0629\u060c \u0645\u0645\u0627 \u064a\u0624\u062f\u064a \u0625\u0644\u0649 \u0632\u064a\u0627\u062f\u0629 \u0642\u062f\u0631\u0629 \u0627\u0644\u062c\u0647\u0627\u0632 \u0627\u0644\u0645\u0646\u0627\u0639\u064a \u0641\u064a \u0643\u0634\u0641 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0633\u0631\u0637\u0627\u0646\u064a\u0629 \u0648\u0627\u0644\u0642\u0636\u0627\u0621 \u0639\u0644\u064a\u0647\u0627<span dir=\"LTR\">.<\/span><\/span><\/p>\n<p dir=\"RTL\" style=\"text-align: justify;\"><span style=\"color:#FF8C00;\">\u0643\u064a\u0641 \u064a\u0639\u0645\u0644 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0645\u0646\u0627\u0639\u064a \u0644\u0644\u0633\u0631\u0637\u0627\u0646\u061f<\/span><\/p>\n<p dir=\"RTL\" style=\"text-align: justify;\">\u064a\u062d\u062a\u0648\u064a \u062c\u0647\u0627\u0632 \u0627\u0644\u0645\u0646\u0627\u0639\u0629 \u0644\u062f\u0649 \u0627\u0644\u0627\u0646\u0633\u0627\u0646 \u0639\u0644\u0649 \u062e\u0644\u0627\u064a\u0627 <span dir=\"LTR\">T<\/span> \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629 \u0623\u0648 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062a\u0627\u0626\u064a\u0629 \u0627\u0644\u062a\u064a \u062a\u0633\u0627\u0639\u062f \u0639\u0644\u0649 \u0645\u062d\u0627\u0631\u0628\u0629 \u0627\u0644\u0623\u0645\u0631\u0627\u0636. \u0648\u064a\u0634\u0628\u0647 \u0639\u0645\u0644\u0647\u0627 \u0639\u0645\u0644 \u0627\u0644\u062c\u0646\u0648\u062f \u0627\u0644\u0630\u064a\u0646 \u064a\u0633\u0627\u0639\u062f\u0648\u0646 \u0627\u0644\u062c\u0633\u0645 \u0639\u0644\u0649 \u0645\u062d\u0627\u0631\u0628\u0629 \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u0627\u062a \u0648\u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0623\u062e\u0631\u0649\u060c \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 \u0627\u0644\u0633\u0631\u0637\u0627\u0646.<\/p>\n<p dir=\"RTL\" style=\"text-align: justify;\">\u0644\u0643\u0646 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0633\u0631\u0637\u0627\u0646\u064a\u0629 \u0637\u0648\u0651\u0631\u062a \u0644\u0646\u0641\u0633\u0647\u0627 \u0648\u0633\u0627\u0626\u0644 \u0644\u0644\u0647\u0631\u0648\u0628 \u0645\u0646 \u0647\u0630\u0627 \u0627\u0644\u0647\u062c\u0648\u0645 \u0639\u0646 \u0637\u0631\u064a\u0642 \u0622\u0644\u064a\u0627\u062a \u062a\u0639\u0645\u0644 \u0645\u062b\u0644 \u0639\u0644\u0627\u0645\u0629 \u0642\u0641 \u0644\u0625\u0644\u063a\u0627\u0621 \u062a\u0646\u0634\u064a\u0637 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062a\u0627\u0626\u064a\u0629. \u0648\u0644\u0642\u062f \u0623\u062b\u0628\u062a \u0627\u0644\u0628\u0627\u062d\u062b\u0648\u0646 \u0625\u0646\u0647 \u064a\u0645\u0643\u0646 \u0645\u0646\u0639 \u0627\u0644\u0639\u0646\u0627\u0635\u0631 \u0627\u0644\u0631\u0626\u064a\u0633\u064a\u0629 \u0644\u0647\u0630\u0647 \u0627\u0644\u0622\u0644\u064a\u0627\u062a\u060c \u0628\u0627\u0633\u062a\u0639\u0645\u0627\u0644 \u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a \u064a\u0637\u0644\u0642 \u0639\u0644\u064a\u0647\u0627 &quot;\u0646\u0642\u0627\u0637 \u0627\u0644\u062a\u0641\u062a\u064a\u0634<span dir=\"LTR\">&quot;<\/span> \u0645\u062b\u0644 \u0627\u0644\u062a\u0635\u0627\u0642 &quot;\u0631\u0627\u0628\u0637 \u0628\u0631\u0648\u062a\u064a\u0646 \u0645\u0648\u062a \u0627\u0644\u062e\u0644\u064a\u0629 \u0627\u0644\u0645\u0628\u0631\u0645\u062c 1 \u06482&quot; &nbsp;<span dir=\"LTR\">PD-L1\/2<\/span> \u0648 <span dir=\"LTR\">CTLA-4,<\/span>\u0648<span dir=\"LTR\">VISTA <\/span>&nbsp;&nbsp;\u0628\u0628\u0631\u0648\u062a\u064a\u0646 &quot;\u0645\u0648\u062a \u0627\u0644\u062e\u0644\u064a\u0629 \u0627\u0644\u0645\u0628\u0631\u0645\u062c 1&quot; &quot;<span dir=\"LTR\">Programmed cell death protein 1<\/span>&nbsp; &nbsp;\u0623\u0648<span dir=\"LTR\">PD-1<\/span> \u060c \u0639\u0646 \u0637\u0631\u064a\u0642 \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a\u060c \u0627\u0644\u062a\u064a \u062a\u0633\u0645\u0649 &quot;\u0645\u062b\u0628\u0637\u0627\u062a \u0646\u0642\u0627\u0637 \u0627\u0644\u062a\u0641\u062a\u064a\u0634 \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629&quot;. \u0648\u0645\u0646 \u062b\u0645 \u0641\u0625\u0646 \u062a\u0646\u0634\u064a\u0637 \u0647\u0630\u0647 \u0627\u0644\u0645\u0643\u0627\u0628\u062d \u064a\u0639\u064a\u062f \u062a\u0646\u0634\u064a\u0637 \u062c\u0647\u0627\u0632 \u0627\u0644\u0645\u0646\u0627\u0639\u0629\u060c \u0648\u0628\u0627\u0644\u062a\u0627\u0644\u064a \u064a\u0633\u0645\u062d \u0644\u0647 \u0628\u0645\u062d\u0627\u0631\u0628\u0629 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0648\u0631\u0645 \u0628\u0634\u0643\u0644 \u0623\u0643\u062b\u0631 \u0641\u0639\u0627\u0644\u064a\u0629<span dir=\"LTR\">.<\/span><\/p>\n<p dir=\"RTL\" style=\"text-align: justify;\">\u0645\u0646 \u0623\u0647\u0645 \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629 \u0644\u0644\u0633\u0631\u0637\u0627\u0646\u0627\u062a \u0648\u0623\u0646\u062c\u062d\u0647\u0627 \u0627\u0644\u0645\u0636\u0627\u062f\u0627\u062a \u0627\u0644\u062c\u0633\u064a\u0645\u064a\u0629 \u0623\u062d\u0627\u062f\u064a\u0629 \u0627\u0644\u0641\u0633\u064a\u0644\u0629 <span dir=\"LTR\">(Monoclonal<\/span> <span dir=\"LTR\">Antibodies)<\/span> \u0644\u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a \u0645\u0647\u0645\u0629 \u0648\u0647\u064a&nbsp;<span dir=\"LTR\">:<\/span> <span dir=\"LTR\">PD-1<\/span> \u0648 <span dir=\"LTR\">PD-L1<\/span> \u0648 <span dir=\"LTR\">PD-L2<\/span>. \u0648\u0642\u062f \u0635\u0627\u062f\u0642\u062a \u0639\u0644\u064a\u0647\u0627 \u0645\u0646\u0638\u0645\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 \u0645\u0646\u0630 \u0633\u0646\u0648\u0627\u062a \u0648\u062a\u0639\u062a\u0645\u062f \u0628\u0646\u062c\u0627\u062d \u0641\u064a \u0627\u0644\u0645\u0631\u0627\u062d\u0644 \u0627\u0644\u0645\u062a\u0623\u062e\u0631\u0629 \u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0633\u0631\u0637\u0627\u0646.&nbsp;&nbsp;<\/p>\n<p dir=\"RTL\" style=\"text-align: justify;\">\u064a\u062a\u0631\u0643\u0632 \u0628\u0631\u0648\u062a\u064a\u0646 \u0627\u0644\u0645\u0648\u062a \u0627\u0644\u062e\u0644\u0648\u064a \u0627\u0644\u0645\u0628\u0631\u0645\u062c 1 \u0623\u0648 <span dir=\"LTR\">PD-1<\/span>&nbsp; \u0639\u0644\u0649 \u0623\u0633\u0637\u062d \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0645\u0646\u0627\u0639\u0629 \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 \u0627\u0644\u062a\u0627\u0626\u064a\u0629 \u0645\u0646\u0647\u0627 \u0648\u064a\u062a\u062d\u0643\u0645 \u0641\u064a \u062a\u0642\u0644\u064a\u0635 \u062a\u062c\u0627\u0648\u0628 \u062c\u0647\u0627\u0632 \u0627\u0644\u0645\u0646\u0627\u0639\u0629 \u062a\u062c\u0627\u0647 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0633\u0645 \u0628\u062a\u062b\u0628\u064a\u0637 \u062f\u0648\u0631 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062a\u0627\u0626\u064a\u0629 \u0641\u064a \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u0627\u062a.&nbsp;<\/p>\n<p dir=\"RTL\" style=\"text-align: justify;\">\u0623\u0645\u0627 \u0631\u0627\u0628\u0637 \u0628\u0631\u0648\u062a\u064a\u0646 \u0645\u0648\u062a \u0627\u0644\u062e\u0644\u064a\u0629 \u0627\u0644\u0645\u0628\u0631\u0645\u062c 1&quot; &quot;<span dir=\"LTR\">Programmed death ligant1<\/span> <span dir=\"LTR\">&quot;<\/span><span dir=\"LTR\">PD-L1.<\/span> \u0623\u0648 (\u0645\u0631\u0643\u0628 \u0627\u0644\u0645\u0648\u062a \u0627\u0644\u0645\u0628\u0631\u0645\u062c) \u0641\u062a\u0639\u0645\u0644 \u0639\u0644\u0649 \u062a\u062b\u0628\u064a\u0637 \u0639\u0645\u0644 \u0627\u0644\u0645\u0646\u0627\u0639\u0629 \u0627\u0644\u0645\u0643\u062a\u0633\u0628\u0629 \u0641\u064a \u0639\u062f\u0629 \u062d\u0627\u0644\u0627\u062a \u0645\u062b\u0644 \u0627\u0644\u062d\u0645\u0644 \u0648\u0632\u0631\u0627\u0639\u0629 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0623\u0648 \u0627\u0644\u0623\u0639\u0636\u0627\u0621<span dir=\"LTR\">. <\/span>&nbsp;\u0648\u0647\u064a \u062a\u062a\u0648\u0627\u062c\u062f \u0639\u0644\u0649 \u0633\u0637\u062d \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629 \u0648\u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0623\u062e\u0631\u0649 \u0641\u064a \u0627\u0644\u0628\u064a\u0626\u0629 \u0627\u0644\u062f\u0642\u064a\u0642\u0629 \u0644\u0644\u0648\u0631\u0645 \u0648\u0644\u0643\u0646\u0647\u0627 \u0645\u0648\u062c\u0648\u062f\u0629 \u0623\u064a\u0636\u0627 \u062e\u0627\u0631\u062c \u0627\u0644\u062e\u0644\u064a\u0629 \u0639\u0644\u0649 \u0627\u0644\u0627\u0643\u0632\u0648\u0633\u0648\u0645\u0627\u062a <span dir=\"LTR\">&nbsp;exosomes<\/span>\u060c&nbsp; \u0648\u0647\u064a \u062d\u0648\u064a\u0635\u0644\u0627\u062a \u062a\u0648\u062c\u062f \u062e\u0627\u0631\u062c \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0641\u064a \u0627\u0644\u0639\u062f\u064a\u062f \u0645\u0646 \u0627\u0644\u0633\u0648\u0627\u0626\u0644 \u0627\u0644\u062d\u064a\u0648\u064a\u0629.<\/p>\n<p dir=\"RTL\" style=\"text-align: justify;\">&nbsp;\u0628\u064a\u0646\u0645\u0627 \u062a\u062a\u0631\u0643\u0632 \u0631\u0648\u0627\u0628\u0637 &quot;\u0628\u0631\u0648\u062a\u064a\u0646 \u0645\u0648\u062a \u0627\u0644\u062e\u0644\u064a\u0629 \u0627\u0644\u0645\u0628\u0631\u0645\u062c2&quot;&nbsp; <span dir=\"LTR\">PDL2<\/span> \u0647\u0648 \u0645\u0646\u0627\u0641\u0633 \u0644\u0644\u0628\u0631\u0648\u062a\u064a\u0646 \u0631\u0642\u0645 \u0648\u0627\u062d\u062f \u062d\u0648\u0644 \u0627\u0644\u0627\u0644\u062a\u0635\u0627\u0642 \u0628\u0628\u0631\u0648\u062a\u064a\u0646 <span dir=\"LTR\">PD-1<\/span> \u0648\u0627\u0644\u0639\u0645\u0644 \u0639\u0644\u0649 \u062a\u062b\u0628\u064a\u0637 \u062a\u0643\u0627\u062b\u0631 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062a\u0627\u0626\u064a\u0629 \u0648 \u062a\u062a\u0631\u0643\u0632 \u0643\u0644 \u0645\u0646\u0647\u0645\u0627 \u0639\u0644\u0649 \u0633\u0637\u062d \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0633\u0631\u0637\u0627\u0646\u064a\u0629.&nbsp;<\/p>\n<p dir=\"RTL\" style=\"text-align: justify;\">\u0648\u062a\u062a\u0645\u062b\u0644 \u0625\u062d\u062f\u0649 \u0637\u0631\u0642 \u0639\u0644\u0627\u062c \u0627\u0644\u0633\u0631\u0637\u0627\u0646 \u0641\u064a \u062a\u062b\u0628\u064a\u0637 \u0627\u0644\u062a\u0641\u0627\u0639\u0644 \u0628\u064a\u0646 <span dir=\"LTR\">PD1<\/span> \u0648\u0623\u062d\u062f \u0645\u0631\u0643\u0628\u0627\u062a\u0647 \u0627\u0644\u0625\u062b\u0646\u064a\u0646 \u0639\u0646 \u0637\u0631\u064a\u0642 \u0625\u062d\u0628\u0627\u0637 \u0639\u0645\u0644\u064a\u0629 \u0627\u0644\u0627\u0644\u062a\u0635\u0627\u0642 \u0628\u064a\u0646\u0647\u0645\u0627 \u0628\u0627\u0644\u0645\u0636\u0627\u062f\u0627\u062a \u0627\u0644\u062c\u0633\u064a\u0645\u064a\u0629 \u0623\u062d\u0627\u062f\u064a\u0629 \u0627\u0644\u0641\u0633\u064a\u0644\u0629\u060c \u0648\u0645\u0646\u0639\u0647\u0627 \u0628\u0627\u0644\u062a\u0627\u0644\u064a \u0645\u0646 \u062a\u0639\u0637\u064a\u0644 \u0639\u0645\u0644 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062a\u0627\u0626\u064a\u0629 \u0641\u064a \u0642\u062a\u0644 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0633\u0631\u0637\u0627\u0646\u064a\u0629.<\/p>\n<p dir=\"RTL\" style=\"text-align: justify;\"><span style=\"color:#FF8C00;\">\u0645\u0631\u0643\u0628\u0627\u062a \u0627\u0644\u0645\u0648\u062a \u0627\u0644\u0645\u0628\u0631\u0645\u062c \u0623\u0646\u0648\u0627\u0639\u0647\u0627 \u0648\u0623\u0647\u0645\u064a\u062a\u0647\u0627<\/span><\/p>\n<p dir=\"RTL\" style=\"text-align: justify;\">\u0641\u064a \u062f\u0631\u0627\u0633\u0629 \u0639\u0644\u0645\u064a\u0629 \u0635\u062f\u0631\u062a \u0641\u064a \u0645\u062c\u0644\u0629 \u0646\u064a\u062a\u0634\u0631 \u0627\u0644\u0639\u0644\u0645\u064a\u0629 \u0641\u064a \u0634\u0647\u0631 \u064a\u0646\u0627\u064a\u0631 <span dir=\"LTR\">2020<\/span> \u0633\u0644\u0637\u062a \u0627\u0644\u0628\u0627\u062d\u062b\u0629 \u0627\u0644\u062a\u0648\u0646\u0633\u064a\u0629 \u0627\u0644\u0645\u0647\u0646\u062f\u0633\u0629 \u0627\u0644\u062f\u0643\u062a\u0648\u0631\u0629 \u0636\u062d\u0649 \u0627\u0644\u062f\u0639\u0627\u0633\u064a \u0627\u0644\u062a\u064a \u062a\u0639\u0645\u0644 \u0643\u0628\u0627\u062d\u062b\u0629 \u0641\u064a \u0643\u0644\u064a\u0629 \u0627\u0644\u0637\u0628 \u0628\u062c\u0627\u0645\u0639\u0629 \u0647\u0627\u0631\u0641\u0631\u062f \u0645\u0639 \u0627\u062b\u0646\u064a\u0646 \u0645\u0646 \u0623\u0643\u0628\u0631 \u0627\u0644\u0628\u0627\u062d\u062b\u064a\u0646 \u0641\u064a \u0645\u062c\u0627\u0644 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0645\u0646\u0627\u0639\u064a \u0641\u064a \u0627\u0644\u0639\u0627\u0644\u0645 \u0647\u0645\u0627 \u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0633\u0648\u0631 \u063a\u0648\u0631\u062f\u0646 \u0641\u0631\u064a\u0645\u0627\u0646 \u0627\u0644\u0645\u0631\u0634\u062d \u0627\u0644\u0628\u0627\u0631\u0632 \u0644\u062c\u0627\u0626\u0632\u0629 \u0646\u0648\u0628\u0644 \u0641\u064a \u0627\u0644\u0637\u0628 \u0644\u0639\u0627\u0645 2018 \u0648\u0643\u0627\u062b\u0644\u064a\u0646 \u0645\u0627\u0647\u0648\u0646\u064a \u060c \u0627\u0644\u0636\u0648\u0621 \u0639\u0644\u0649 \u0623\u0646\u0648\u0627\u0639 &quot;\u0631\u0627\u0628\u0637 \u0628\u0631\u0648\u062a\u064a\u0646 \u0645\u0648\u062a \u0627\u0644\u062e\u0644\u064a\u0629 \u0627\u0644\u0645\u0628\u0631\u0645\u062c 1&quot; <span dir=\"LTR\">PD-L1.<\/span> \u0648\u0623\u0647\u0645\u064a\u062a\u0647\u0627 \u0641\u064a \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0645\u0646\u0627\u0639\u064a \u0644\u0644\u0633\u0631\u0637\u0627\u0646\u0627\u062a.<\/p>\n<p dir=\"RTL\" style=\"text-align: justify;\">\u062a\u0642\u0648\u0644 \u0627\u0644\u0628\u0627\u062d\u062b\u0629 \u0627\u0644\u062a\u0648\u0646\u0633\u064a\u0629 \u0636\u062d\u0649 \u0627\u0644\u062f\u0639\u0627\u0633\u064a \u0625\u0646 &quot; \u0627\u0644\u0647\u062f\u0641 \u0645\u0646 \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0647\u0648 \u062a\u0642\u062f\u064a\u0645 \u0623\u0647\u0645 \u0645\u0627 \u062a\u0648\u0635\u0644 \u0625\u0644\u064a\u0647 \u0627\u0644\u0628\u062d\u062b \u0627\u0644\u0639\u0644\u0645\u064a \u0641\u064a \u0645\u062c\u0627\u0644 \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629 \u0644\u0644\u0633\u0631\u0637\u0627\u0646\u0627\u062a \u0639\u0644\u0649 \u0636\u0648\u0621 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0627\u0644\u062a\u064a \u062a\u0648\u0635\u0644\u062a \u0625\u0644\u064a\u0647\u0627 \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u0639\u0644\u0645\u064a\u0629 \u0627\u0644\u0633\u0627\u0628\u0642\u0629 \u062d\u0648\u0644 \u0645\u0631\u0643\u0628\u0627\u062a \u0627\u0644\u0645\u0648\u062a \u0627\u0644\u0645\u0628\u0631\u0645\u062c <span dir=\"LTR\">PDL1 <\/span>&nbsp;\u0648<span dir=\"LTR\">PDL2 <\/span>&nbsp;\u0639\u0646\u062f \u0627\u0644\u062a\u062d\u0627\u0645\u0647\u0627 \u062f\u0627\u062e\u0644 \u0627\u0644\u0645\u062d\u064a\u0637 \u0627\u0644\u0645\u0635\u063a\u0631 \u0644\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0645\u0635\u0627\u0628\u0629 \u0628\u0627\u0644\u0633\u0631\u0637\u0627\u0646&nbsp; \u0645\u0639 \u0645\u0633\u062a\u0642\u0628\u0644\u0647\u0627 &quot;\u0628\u0631\u0648\u062a\u064a\u0646 \u0645\u0648\u062a \u0627\u0644\u062e\u0644\u064a\u0629 \u0627\u0644\u0645\u0628\u0631\u0645\u062c 1&quot; &quot;<span dir=\"LTR\">Programmed cell death protein 1<\/span>&nbsp; \u0623\u0648<span dir=\"LTR\">PD-1<\/span>&quot; \u0628\u0627\u0644\u062a\u0631\u0643\u064a\u0632 \u0639\u0644\u0649 \u0627\u0644\u0631\u0627\u0628\u0637 \u0645\u0646 \u0627\u0644\u0646\u0648\u0639 \u0627\u0644\u0623\u0648\u0644 \u0627\u0644\u062a\u064a \u0645\u0646\u0647\u0627 \u0645\u0627 \u0647\u0648 \u0630\u0627\u0626\u0628 \u0641\u064a \u0633\u0648\u0627\u0626\u0644 \u0627\u0644\u062c\u0633\u0645 \u0643\u0627\u0644\u062f\u0645\u060c \u0648\u0623\u0647\u0645\u0647\u0627 \u0628\u0627\u0644\u062a\u062d\u062f\u064a\u062f \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a \u0627\u0644\u0645\u062d\u0645\u0648\u0644\u0629 \u0639\u0628\u0631 \u0627\u0644\u062d\u0648\u064a\u0635\u0644\u0627\u062a \u0627\u0644\u0635\u063a\u064a\u0631\u0629 (<span dir=\"LTR\">exosomes<\/span>).<\/p>\n<p dir=\"RTL\" style=\"text-align: justify;\">\u0648\u062a\u0636\u064a\u0641 \u0627\u0644\u0645\u0624\u0644\u0641\u0629 \u0627\u0644\u0631\u0626\u064a\u0633\u064a\u0629 \u0644\u0647\u0630\u0647 \u0627\u0644\u0648\u0631\u0642\u0629 \u0627\u0644\u0639\u0644\u0645\u064a\u0629 \u0641\u064a \u062d\u0648\u0627\u0631 \u0645\u0639 <a href=\"http:\/\/www.arsco.org\/\">\u0645\u0648\u0642\u0639 \u0645\u0646\u0638\u0645\u0629 \u0627\u0644\u0645\u062c\u062a\u0645\u0639 \u0627\u0644\u0639\u0644\u0645\u064a \u0627\u0644\u0639\u0631\u0628\u064a<\/a> \u0623\u0646 &quot; \u0627\u062e\u062a\u0628\u0627\u0631 &quot;\u0631\u0627\u0628\u0637 \u0628\u0631\u0648\u062a\u064a\u0646 \u0645\u0648\u062a \u0627\u0644\u062e\u0644\u064a\u0629 \u0627\u0644\u0645\u0628\u0631\u0645\u062c<span dir=\"LTR\">1<\/span> <span dir=\"LTR\">PDL1&quot;<\/span> <span dir=\"LTR\">&quot;<\/span> \u064a\u0639\u062f \u0645\u0646 \u0627\u0644\u0627\u062e\u062a\u0628\u0627\u0631\u0627\u062a \u0627\u0644\u0647\u0627\u0645\u0629 \u0627\u0644\u062a\u064a \u064a\u062e\u0636\u0639 \u0644\u0647\u0627 \u0627\u0644\u0645\u0631\u064a\u0636 \u0648\u0627\u0644\u062a\u064a \u062a\u0642\u064a\u0633 \u0645\u0642\u062f\u0627\u0631 \u0647\u0630\u0627 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646 \u0639\u0644\u0649 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0633\u0631\u0637\u0627\u0646\u064a\u0629\u060c \u0641\u0625\u0630\u0627 \u0643\u0627\u0646\u062a \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0633\u0631\u0637\u0627\u0646 \u062a\u062d\u062a\u0648\u064a \u0639\u0644\u0649 \u0646\u0633\u0628\u0629 \u0639\u0627\u0644\u064a\u0629 \u0645\u0646<span dir=\"LTR\"> PDL1<\/span>-\u0648\u0642\u062f \u064a\u062d\u062f\u062b \u0627\u0644\u0639\u0643\u0633 &#8211; \u0641\u0647\u0630\u0627 \u064a\u0639\u0646\u064a \u0625\u0645\u0643\u0627\u0646\u064a\u0629 \u062a\u0642\u062f\u064a\u0645 \u0639\u0644\u0627\u062c \u0645\u0646\u0627\u0639\u064a \u0644\u0644\u0645\u0631\u064a\u0636 \u0644\u064a\u0639\u0632\u0632 \u0646\u0638\u0627\u0645\u0647 \u0627\u0644\u0645\u0646\u0627\u0639\u064a \u0648\u064a\u0633\u0627\u0639\u062f\u0647 \u0639\u0644\u0649 \u0627\u0644\u062a\u0639\u0631\u0641 \u0639\u0644\u0649 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0633\u0631\u0637\u0627\u0646\u064a\u0629 \u0648\u0645\u0643\u0627\u0641\u062d\u062a\u0647\u0627\u060c \u0648\u0642\u062f \u062b\u0628\u062a \u0623\u0646 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0645\u0646\u0627\u0639\u064a \u0641\u0639\u0651\u0627\u0644 \u0644\u0644\u063a\u0627\u064a\u0629 \u0641\u064a \u0639\u0644\u0627\u062c \u0623\u0646\u0648\u0627\u0639 \u0645\u0639\u064a\u0646\u0629 \u0645\u0646 \u0627\u0644\u0633\u0631\u0637\u0627\u0646\u0627\u062a\u060c \u0643\u0645\u0627 \u0623\u0646 \u0644\u0647 \u0622\u062b\u0627\u0631 \u062c\u0627\u0646\u0628\u064a\u0629 \u0623\u0642\u0644 \u0645\u0646 \u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u0623\u062e\u0631\u0649 \u0643\u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a\u0629 \u0645\u0646\u0647\u0627<span dir=\"LTR\">.<\/span>&quot;<\/p>\n<p dir=\"RTL\" style=\"text-align: justify;\">\u064a\u0642\u0648\u0644 \u0627\u0644\u0628\u0627\u062d\u062b\u0648\u0646 \u0625\u0646 \u062a\u0641\u0627\u0639\u0644 \u0645\u0631\u0643\u0628\u0627\u062a \u0627\u0644\u0645\u0648\u062a \u0627\u0644\u0645\u0628\u0631\u0645\u062c (<span dir=\"LTR\">PDL1<\/span>) \u0627\u0644\u0645\u062d\u0645\u0648\u0644\u0629 \u0639\u0628\u0631 \u0627\u0644\u062d\u0648\u064a\u0635\u0644\u0627\u062a \u0627\u0644\u0635\u063a\u064a\u0631\u0629 (<span dir=\"LTR\">exosomes<\/span>) \u062a\u0639\u062f\u0651 \u0627\u0644\u0623\u0643\u062b\u0631 \u0623\u0647\u0645\u064a\u0629 \u0645\u0646 \u062d\u064a\u062b \u0643\u0645\u064a\u062a\u0647\u0627 \u0648\u0641\u0627\u0639\u0644\u064a\u062a\u0647\u0627 \u0645\u0639 \u0628\u0631\u0648\u062a\u064a\u0646 (<span dir=\"LTR\">PD1<\/span>) \u0627\u0644\u0645\u0648\u062c\u0648\u062f \u0639\u0644\u0649 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0645\u0646\u0627\u0639\u0629\u060c \u0648\u0642\u062f \u0642\u0627\u0645\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0628\u0625\u062c\u0631\u0627\u0621 \u0645\u0642\u0627\u0631\u0646\u0629 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a \u0627\u0644\u0630\u0627\u0626\u0628\u0629 \u0628\u0634\u0643\u0644 \u0639\u0627\u0645 \u0645\u0639 \u0627\u0644\u0645\u062d\u0645\u0648\u0644\u0629 \u0639\u0628\u0631 \u0627\u0644\u062d\u0648\u064a\u0635\u0644\u0627\u062a \u0645\u0646 \u062d\u064a\u062b \u0627\u0644\u0648\u0638\u0627\u0626\u0641 \u0627\u0644\u0628\u064a\u0648\u0644\u0648\u062c\u064a\u0629.<\/p>\n<p dir=\"RTL\" style=\"text-align: justify;\">\u062a\u0642\u0648\u0644 \u0627\u0644\u062f\u0643\u062a\u0648\u0631\u0629 \u0636\u062d\u0649 \u0627\u0644\u062f\u0639\u0627\u0633\u064a \u0625\u0646 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0623\u0638\u0647\u0631\u062a \u0623\u0646 &quot; \u0645\u0631\u0643\u0628\u0627\u062a \u0627\u0644\u0645\u0648\u062a \u0627\u0644\u0645\u0628\u0631\u0645\u062c \u0627\u0644\u0630\u0627\u0626\u0628\u0629 \u0627\u0644\u0645\u0633\u062a\u062e\u0631\u062c\u0629 \u0645\u0646 \u062f\u0627\u062e\u0644 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u064a\u0642\u062a\u0635\u0631 \u0645\u062c\u0627\u0644 \u062a\u0623\u062b\u064a\u0631\u0647\u0627 \u0639\u0644\u0649 \u0627\u0644\u062e\u0644\u064a\u0629 \u0627\u0644\u0645\u0635\u0627\u0628\u0629 \u0628\u0627\u0644\u0633\u0631\u0637\u0627\u0646 \u0648\u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0645\u062c\u0627\u0648\u0631\u0629 \u0644\u0647\u0627 \u0631\u063a\u0645 \u0623\u0646\u0647\u0627 \u0627\u0644\u0623\u0643\u062b\u0631 \u0627\u0633\u062a\u062e\u062f\u0627\u0645\u0627 \u0644\u062f\u0649 \u0627\u0644\u0623\u0637\u0628\u0627\u0621 \u0641\u064a \u0627\u062e\u062a\u0628\u0627\u0631\u0627\u062a \u062a\u062d\u062f\u064a\u062f \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0645\u0646\u0627\u0639\u064a \u0644\u0644\u0633\u0631\u0637\u0627\u0646. \u0628\u064a\u0646\u0645\u0627 \u064a\u0645\u062a\u062f \u062a\u0623\u062b\u064a\u0631 \u0645\u0631\u0643\u0628\u0627\u062a \u0627\u0644\u0645\u0648\u062a \u0627\u0644\u0645\u0628\u0631\u0645\u062c <span dir=\"LTR\">PDL1 <\/span>&nbsp;\u0627\u0644\u0627\u0643\u0632\u0648\u0633\u0648\u0645\u064a\u0629 \u0625\u0644\u0649 \u0623\u0628\u0639\u062f \u0645\u0646 \u0630\u0644\u0643\u060c \u0648\u062a\u062a\u0645\u062a\u0639 \u0628\u062e\u0627\u0635\u064a\u0629 \u0627\u0644\u0642\u064a\u0627\u0645 \u0628\u0648\u0638\u0627\u0626\u0641 \u0639\u0646 \u0628\u0639\u062f \u0648\u0647\u064a \u0628\u0630\u0644\u0643 \u0623\u0643\u062b\u0631 \u062f\u0642\u0629 \u0644\u0623\u0646 \u0627\u0644\u0646\u0648\u0639 \u0627\u0644\u0630\u0627\u0626\u0628 \u064a\u0643\u0648\u0646 \u0623\u064a\u0636\u0627\u064b \u0645\u0648\u062c\u0648\u062f \u0641\u064a \u063a\u064a\u0631 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0633\u0631\u0637\u0627\u0646\u064a\u0629 \u0639\u0644\u0649 \u0639\u0643\u0633 \u062a\u0644\u0643 \u0627\u0644\u0645\u0648\u062c\u0648\u062f\u0629 \u0641\u064a \u0627\u0644\u062d\u0648\u064a\u0635\u0644\u0627\u062a &quot; \u0648\u0627\u0633\u062a\u0646\u062a\u062c\u062a \u0627\u0644\u0628\u0627\u062d\u062b\u0629 \u0623\u0646 \u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0647\u0630\u0627 \u0627\u0644\u0646\u0648\u0639 \u0627\u0644\u0623\u062e\u064a\u0631 \u0627\u0644\u0630\u064a \u064a\u062a\u0645\u062a\u0639 \u0628\u062f\u0642\u0629 \u0623\u0643\u0628\u0631 \u064a\u0645\u0643\u0651\u0646 \u0645\u0646 \u0627\u0644\u0645\u0633\u0627\u0639\u062f\u0629 \u0639\u0644\u0649 \u0623\u062e\u0630 \u0627\u0644\u0642\u0631\u0627\u0631 \u0627\u0644\u0645\u0633\u0628\u0642\u060c \u0641\u064a\u0645\u0643\u0651\u0646 \u0628\u0630\u0644\u0643 \u0645\u0646 \u062a\u062d\u062f\u064a\u062f \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0646\u0627\u062c\u0639 \u0644\u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0623\u0646\u0648\u0627\u0639 \u0627\u0644\u0645\u062e\u062a\u0644\u0641\u0629 \u0645\u0646 \u0627\u0644\u0633\u0631\u0637\u0627\u0646\u0627\u062a \u0641\u064a \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644.<\/p>\n<p dir=\"RTL\" style=\"text-align: justify;\"><span style=\"color:#FF8C00;\">\u0646\u0628\u0630\u0629 \u0639\u0646 \u0627\u0644\u0628\u0627\u062d\u062b\u0629<\/span><\/p>\n<p dir=\"RTL\" style=\"text-align: justify;\">\u0627\u0644\u062f\u0643\u062a\u0648\u0631\u0629 \u0636\u062d\u0649 \u0627\u0644\u062f\u0639\u0627\u0633\u064a \u0645\u0647\u0646\u062f\u0633\u0629 \u0641\u064a \u0627\u0644\u0628\u064a\u0648\u0644\u0648\u062c\u064a\u0627 \u0627\u0644\u062d\u064a\u0648\u064a\u0629 \u062d\u0627\u0635\u0644\u0629 \u0639\u0644\u0649 \u0627\u0644\u062f\u0643\u062a\u0648\u0631\u0627\u0647 \u0645\u0646 \u062c\u0627\u0645\u0639\u0629 \u062a\u0633\u0648\u0643\u0648\u0628\u0627 \u0627\u0644\u064a\u0627\u0628\u0627\u0646\u064a\u0629 \u0641\u064a \u0645\u062c\u0627\u0644 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a \u0627\u0644\u0633\u0631\u0637\u0627\u0646\u064a\u0629 \u0648\u062a\u0639\u0628\u064a\u0631\u0647\u0627 \u062f\u0627\u062e\u0644 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629 \u0627\u0644\u0623\u0643\u0644\u0629 \u0623\u0648 \u0627\u0644\u0645\u0633\u0645\u0627\u0629 \u0628\u0627\u0644\u0628\u0644\u0627\u0639\u0645.<\/p>\n<p dir=\"RTL\" style=\"text-align: justify;\"><img decoding=\"async\" alt=\"\" src=\"http:\/\/arsco.org\/wp-content\/uploads\/EditorImages\/NewImages\/SharedScreenshot180420051625.jpg\" style=\"margin: 5px; width: 400px; height: 265px; float: left;\" \/>\u062a\u0639\u0645\u0644 \u062d\u0627\u0644\u064a\u0627 \u0643\u0628\u0627\u062d\u062b\u0629 \u0645\u0627 \u0628\u0639\u062f \u0627\u0644\u062f\u0643\u062a\u0648\u0631\u0627\u0647 <span dir=\"LTR\">&nbsp;postdoc<\/span>\u0641\u064a \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629 \u0641\u064a \u0643\u0644\u064a\u0629 \u0627\u0644\u0637\u0628 \u0628\u062c\u0627\u0645\u0639\u0629 \u0647\u0627\u0631\u0641\u0627\u0631\u062f \u0648\u062a\u0642\u0648\u0645 \u0628\u0625\u062c\u0631\u0627\u0621 \u0627\u0644\u0632\u0645\u0627\u0644\u0629 \u0627\u0644\u0628\u062d\u062b\u064a\u0629 \u0641\u064a <span dir=\"LTR\">Massachusets G&eacute;n&eacute;ral Hospital<\/span> \u0639\u0644\u0649 \u0627\u0644\u0645\u0633\u062a\u0636\u062f\u0627\u062a \u0627\u0644\u062c\u062f\u064a\u062f\u0629 <span dir=\"LTR\">Neoantigens<\/span> \u0628\u0647\u062f\u0641 \u062f\u0631\u0627\u0633\u0629 \u0644\u0642\u0627\u062d\u0627\u062a \u0644\u0644\u0633\u0631\u0637\u0627\u0646.<\/p>\n<p dir=\"RTL\" style=\"text-align: justify;\">\u0639\u0645\u0644\u062a \u0642\u0628\u0644 \u0630\u0644\u0643 \u0643\u0628\u0627\u062d\u062b\u0629 \u0641\u064a \u0645\u062c\u0627\u0644 \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629 \u0644\u0644\u0633\u0631\u0637\u0627\u0646\u0627\u062a \u0648\u0627\u0634\u062a\u063a\u0644\u062a \u0639\u0644\u0649 \u0646\u0642\u0627\u0637 \u0627\u0644\u062a\u0641\u062a\u064a\u0634 \u0627\u0644\u0645\u0646\u0627\u0639\u064a \u0645\u0639 \u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0633\u0648\u0631 \u063a\u0648\u0631\u062f\u0646 \u0641\u0631\u064a\u0645\u0627\u0646 \u0645\u0643\u062a\u0634\u0641 \u0637\u0631\u064a\u0642\u0629 \u0639\u0645\u0644 \u0645\u0631\u0643\u0628\u0627\u062a \u0627\u0644\u0645\u0648\u062a \u0627\u0644\u0645\u0628\u0631\u0645\u062c <span dir=\"LTR\">PDL1 ,2<\/span> \u0627\u0644\u0645\u0633\u062a\u062e\u062f\u0645\u0629 \u0641\u064a \u0639\u0644\u0627\u062c \u0627\u0644\u0633\u0631\u0637\u0627\u0646\u0627\u062a \u0623\u062d\u062f \u0623\u0643\u062b\u0631 \u0627\u0644\u0623\u062f\u0648\u0627\u062a \u0627\u0644\u0645\u0633\u062a\u062e\u062f\u0645\u0629 \u062d\u0627\u0644\u064a\u0627 \u0641\u064a \u0639\u0644\u0627\u062c \u0627\u0644\u0633\u0631\u0637\u0627\u0646\u0627\u062a \u0641\u064a<span dir=\"LTR\"> Dana Farber Cancer institute <\/span>\u0648\u0647\u0648 \u0645\u0633\u062a\u0634\u0641\u0649 \u0622\u062e\u0631 \u062a\u0627\u0628\u0639&nbsp; \u0644\u0643\u0644\u064a\u0629 \u0627\u0644\u0637\u0628 \u0628\u062c\u0627\u0645\u0639\u0629 \u0647\u0627\u0631\u0641\u0627\u0631\u062f <span dir=\"LTR\">.<\/span><\/p>\n<p dir=\"RTL\" style=\"text-align: justify;\">&nbsp;<\/p>\n<p dir=\"RTL\" style=\"text-align: justify;\"><span style=\"color:#FF8C00;\">\u0627\u0644\u0645\u0635\u0627\u062f\u0631<\/span><\/p>\n<ul>\n<li dir=\"ltr\" style=\"text-align: left;\"><a href=\"https:\/\/www.nature.com\/articles\/s41577-019-0264-y?fbclid=IwAR0YfGVSKA6MYHk0zK-aHQfTh3zRm_3a3wAoMFSiVgSQY2xKcC0IRdcjoHI\">https:\/\/www.nature.com\/articles\/s41577-019-0264-y?fbclid=IwAR0YfGVSKA6MYHk0zK-aHQfTh3zRm_3a3wAoMFSiVgSQY2xKcC0IRdcjoHI<\/a><\/li>\n<li dir=\"ltr\" style=\"text-align: left;\"><a href=\"https:\/\/connects.catalyst.harvard.edu\/Profiles\/display\/Person\/122834\">https:\/\/connects.catalyst.harvard.edu\/Profiles\/display\/Person\/122834<\/a><\/li>\n<li dir=\"ltr\" style=\"text-align: left;\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/?term=gordon+j+freeman\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/?term=gordon+j+freeman<\/a><\/li>\n<\/ul>\n<ul>\n<li style=\"text-align: right;\">\u062d\u0648\u0627\u0631 \u0645\u0639 \u0627\u0644\u0628\u0627\u062d\u062b\u0629 \u0623\u062c\u0631\u062a\u0647 \u0645\u0646\u0638\u0645\u0629 \u0627\u0644\u0645\u062c\u062a\u0645\u0639 \u0627\u0644\u0639\u0644\u0645\u064a \u0627\u0644\u0639\u0631\u0628\u064a.<\/li>\n<\/ul>\n<p style=\"text-align: justify;\">\n&nbsp;<\/p>\n<p style=\"text-align: justify;\"><span style=\"color:#FF8C00;\">\u0627\u0644\u0628\u0631\u064a\u062f \u0627\u0644\u0627\u0644\u0643\u062a\u0631\u0648\u0646\u064a \u0644\u0644\u0643\u0627\u062a\u0628:<\/span>&nbsp;<a href=\"mailto:gharbis@gmail.com\">gharbis@gmail.com<\/a><\/p>\n","protected":false},"featured_media":0,"menu_order":805,"comment_status":"open","ping_status":"open","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0},"tags":[11163,11708,13442],"class_list":["post-15728","articles","type-articles","status-publish","hentry","tag-11163","tag-11708","tag-13442"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u0646\u0638\u0631\u0629 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